Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 947-377-6
CAS number: -
In an acute oral toxicity study performed
according to the OECD Guideline 420 and in compliance with GLP, a single
dose of 2000 mg/kg bw of the test substance was given by oral gavage to
a group of 5 female Sprague Dawley rats. Animals were then observed for
mortality, clinical signs and body weight changes for 14 days, and were
all sacrificed for macroscopic examinations.
No mortality occurred during the study. No
clinical signs related to the administration of the test item were
observed during the study, except for an increase in salivation noted in
two animals (2/5) only at 30 minutes post-dose. The body weight
evolution of the animals remained normal throughout the study. The
macroscopic examination of the animals at the end of the study did not
reveal treatment related changes.
Rat Oral LD50 >2000 mg/kg bw.
Under the test conditions, the oral LD50 of
the test substance is >2000 mg/kg bw in rats. In accordance with
Regulation (EC) No. 1272/2008 on classification, labelling and packaging
substances and mixtures, the test item does not have to be classified.
No signal word or hazard statement is required.
In accordance with Globally Harmonised
System of classification and labelling of chemicals (GHS), the test item
Boswellia serrata extract has to be classified in Category 5 with the
signal word “Warning” and the hazard statement “H303 May be Harmful if
swallowed” or does not have to be classified with no signal word or
hazard statement required.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Sellel veebilehel kasutatakse küpsiseid, et tagada lehe parim kasutus.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again