Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 205-205-0 | CAS number: 135-61-5
Direct observations: clinical cases, poisoning incidents and other
Administrative data
- Endpoint:
- direct observations: clinical cases, poisoning incidents and other
- Type of information:
- other: case report
- Adequacy of study:
- supporting study
- Study period:
- 1986
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Case report, abstract only; very limited documentation, insufficient detail, data on source incomplete
Data source
Reference
- Reference Type:
- publication
- Title:
- Mutual relation between patch test reactions and chemical structures of Naphtol AS and its derivatives
- Author:
- Arima, Y.; Matsunaga, K.; Hayakawa, R.; Kojima, S.; Kaniwa,M.; Nakamura, A.
- Year:
- 1 986
- Bibliographic source:
- Hifu 28 (extra issue 2): 246-259 (1986)
Materials and methods
- Study type:
- clinical case study
- Endpoint addressed:
- skin sensitisation
Test guideline
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- case report
- GLP compliance:
- no
Test material
- Reference substance name:
- Automatically generated during migration to IUCLID 6, no data available
- IUPAC Name:
- Automatically generated during migration to IUCLID 6, no data available
- Details on test material:
- Naphtol AS derivatives
Constituent 1
Method
- Type of population:
- general
- Subjects:
- 2 cases; no further data
- Ethical approval:
- not applicable
- Route of exposure:
- dermal
- Reason of exposure:
- unintentional, non-occupational
- Exposure assessment:
- not specified
Results and discussion
- Clinical signs:
- contact dermatitis
Applicant's summary and conclusion
- Conclusions:
- Inconclusive as the substance responsible for the effects is not clearly identified
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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