Registration Dossier
Registration Dossier
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EC number: 939-719-8 | CAS number: 5502-75-0
PBT assessment
Administrative data
PBT assessment: overall result
- Name:
- Reaction Mass of Cis-4-(isopropyl) cyclohexanemethanol and Trans-4-(isopropyl) cyclohexanemethanol
- Type of composition:
- legal entity composition of the substance
- State / form:
- liquid
- Reference substance:
- Reaction Mass of Cis-4-(isopropyl) cyclohexanemethanol and Trans-4-(isopropyl) cyclohexanemethanol
- Reference substance:
- Reaction Mass of Cis-4-(isopropyl) cyclohexanemethanol and Trans-4-(isopropyl) cyclohexanemethanol
- PBT status:
- the substance is not PBT / vPvB
- Justification:
The substance has been tested for biodegradability and bioaccumulation potential (Log Pow) and has been shown not to fulfil the screening criteria for P/vP or B/vB. In addition, two QSARs models were used in a weight of evidence approach to determine the bioconcentration factor (BCF) of the registered substance, and based on these predictions, the key BCF value is estimated at 81.5 L/kg, well lower than the B criteria.
While a full dataset on chronic aquatic toxicity data is not available, the substance is not considered toxic based on consideration of the acute aquatic toxicity data (including results of studies in algae, daphnia and fish per OECD 201, 202, and 203), which do not fulfil the screening criteria for toxicity based on the EC50 values of these studies and the chronic toxicity data from the algal test (72h EC10 for growth is 5.2 mg/L). No toxicity to humans is known for the substance. Based on the available information, the substance is not classified as having CMR properties, nor does it show other evidence of toxicities based on a sub-chronic toxicity study in animals.
Thus, the substance is considered neither PBT nor vPvB.
Reference
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