Registration Dossier
Registration Dossier
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EC number: 421-140-2 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
48h EC50 > 102 mg/L
NOEC >= 102 mg/L
Key value for chemical safety assessment
Additional information
Two studies are available assessing the acute toxicity of RSS-4 to aquatic invertebrates. The key study (rated Klimish 1) is an acute toxicity study on Daphnia magna (1997) according to an internationally accepted protocol and performed under GLP conditions. The other study (1982, rated Klimish 2) was also performed under GLP conditions and according to internationally accepted protocols. However, the composition of the test sample is not described sufficiently in the test reports.
In the key study, the acute toxicity of RSS-4 to Daphnia magna was assessed under static exposure conditions over a period of 48 hours using internationally accepted methods. The results of the chemical analysis indicated that the intended exposure level was adequately achieved and maintained during the test, giving an overall mean measured level of 102 mg/L.
No treatment-related effects or immobilities were observed on the Daphnia during the test. The 48-hour EC50 value could not be identified and must be > 102 mg/L. The NOEC was considered to be >= 102 mg/L.
RSS-4 was not considered to be acutely toxic to Daphnia magna when dissolved in water at 102 mg/L (measured concentration).
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