Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 411-080-5 | CAS number: -
Endpoint summary
Administrative data
Description of key information
In 2 valid studies Pigment Yellow FC 26290 was tested for skin irritation/corrosion and eye irritation. The test substance was found to be not irritating to the skin and not irritating to the eye
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
The test substance was tested in a 4 h skin irritation/corrosion test in rabbits. The test substance (500 mg) was semi-occlusively applied once to the intact skin of 3 rabbits and remained there for 4 hours. The animals were observed for 7 days after experiment. Mean value for erythema according to DRAIZE was: 0.0; mean value for edema: 0.0. The test substance was found to be not irritating.
The test substance was tested in a 24 h eye irritation test in rabbits. The test substance (100 µl = ca. 32 mg) was administered into one eye of 3 rabbits (the other eye remained untreated and served as control). The substance was washed out after 24 hours with normal saline. The animals were observed for 7 days after experiment. Signs of irritation proved to be fully reversible within 7 days.
The test substance was found to be not irritating to eye.
Justification for classification or non-classification
skin irritation:
mean value for erythema = 0, mean value for oedema = 0
On the basis of this data a classification is not justified
eye irritation:
mean values for cornea opacity (0); mean values for iris inflammation (0);
mean values for conjunctivae reddening (0.2), mean values for conjunctivae swelling (0.6)
On the basis of this data a classification is not justified
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
