Registration Dossier
Registration Dossier
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EC number: 411-080-5 | CAS number: -
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
No studies are available on toxicokinetics, metabolism and distribution. In the acute oral toxicity and the acute dermal toxicity studies the LD50 are >2000 mg/kg bw. No signs of intoxication or systemic poisoning were observed. In a subacute oral toxicity study the appearance and general behaviour was not influenced by treatment up to and including 1000 mg/kg. The general condition was temporarily reduced in some animals of the dose group 1000 mg/kg. Growth, mortality, feed and water intake were not affected by treatment. Hematological and histopathological investigations gave no indication of toxicologically relevant damage to blood or hematopoietic organs up to and including 1000 mg/kg. Neither clinico-chemical nor gross pathological or histopathological investigations produced any evidence of treatment-related metabolic or organ damage. Therefore absorption and bioavailability of Pigment Yellow FC 26290 seems generally to be limited and bioaccumulation is not expected.
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