alpha-[butyl(dimethylsilyl)]-omega-[3-(2-{[2- (methacryloyloxy)ethyl]carbamoyloxy}ethoxy) propyl]poly[oxy(dimethyl)silylene]

Water solubility

Administrative data

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

01 August - 06 Oct 2005

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: done under GLP and OECD method

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2005

Report date:

2005

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Test guideline 2

Qualifier:

according to guideline

Guideline:

other: other guideline: estimation software WATERNT( US EPA)

Principles of method if other than guideline:

Value determined using a computer estimation as shake flask method was not suitable.

GLP compliance:

yes

Type of method:

flask method

Test material

Test material information

Test material form:

liquid

Results and discussion

Water solubility

Water solubility:

0 g/L

Temp.:

25 °C

Remarks on result:

other: computational estimation

Details on results:

The shake flask definitive test had problems in emulsification and the solution of filtering of the sample to clear this up potentially interferred with the validity of the samples. Therefore no overall result could be determined for the shake flask definitive test. The computer analysis was determined to be valid (+/- 1 log unit and no errors) for the determineation of the water solubility of the test material.

Any other information on results incl. tables

The preliminary water solubility test indicated that the column elution method should have been performed as the solubility was less than 1 x 10-2 g/l. However due to the physical nature of the substance, it was considered not technically possible to use this method. The varying results following shaking and equilibration showed that sample cleanup could not be performed sucessfully due to the fine emulsions formed by the substance. As such method EEC A6 was considered not applicable to this material. The water solubility of the substance has been determined to be less than 6.89 x 10-8 g/l of solution at 25 Deg C, using specialist computer estimation software, WATERNT (TM) (c) 2000 U.S. EPA.

Applicant's summary and conclusion

Conclusions:

Interpretation of results (migrated information): insoluble (< 0.1 mg/L)
The water solubility of the test material was determined based on computational estimation to be 6.89 EE-8 g/L of solution at 25ºC