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Diss Factsheets

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Testing was conducted between 24 June 2011 and 04 July 2011.
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results. The study report was conclusive, done to a valid guideline and the study was conducted under GLP conditions.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2011
Report date:
2011

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: vapour pressure balance

Test material

Test material form:
liquid

Results and discussion

Vapour pressure
Temp.:
25 °C
Vapour pressure:
> 0.009 Pa
Transition / decomposition
Transition / decomposition:
no

Any other information on results incl. tables

Run1

Temperature (ºC)

Temperature (K)

Reciprocal Temperature (K-1)

Mass Difference (µg)

Mass Difference (kg)

Vapour Pressure (Pa)

Log10Vp

21

294.15

0.003399626

0.32

3.200E-10

0.000444242

-3.352380400

22

295.15

0.003388108

6.10

6.100E-09

0.008468363

-2.072200544

23

296.15

0.003376667

0.11

1.100E-10

0.000152708

-3.816137694

25

298.15

0.003354016

9.93

9.930E-09

0.013785384

-1.860581130

27

300.15

0.003331667

1.32

1.320E-09

0.001832498

-2.736956448

28

301.15

0.003320604

2.83

2.830E-09

0.003928765

-2.405743943

29

302.15

0.003309614

2.08

2.080E-09

0.002887573

-2.539467044

30

303.15

0.003298697

2.24

2.240E-09

0.003109694

-2.507282360

No statistical analysis is given due to the nature of the plot.

Run 1 -Graph of Log10Vapour Pressure vs Reciprocal Temperature see Attachment 3 Run 1 to 4.

Run 2

Temperature (ºC)

Temperature (K)

Reciprocal Temperature (K-1)

Mass Difference (µg)

Mass Difference (kg)

Vapour Pressure (Pa)

Log10Vp

20

293.15

0.003411223

3.77

3.770E-09

0.005233726

-2.281189029

22

295.15

0.003388108

7.21

7.210E-09

0.010009327

-1.999595114

23

296.15

0.003376667

1.16

1.160E-09

0.001610377

-2.793072390

24

297.15

0.003365304

7.11

7.110E-09

0.009870502

-2.005660778

25

298.15

0.003354016

1.20

1.200E-09

0.001665907

-2.778349133

26

299.15

0.003342805

7.51

7.510E-09

0.010425804

-1.981890442

27

300.15

0.003331667

2.95

2.950E-09

0.004095356

-2.387708363

28

301.15

0.003320604

9.72

9.720E-09

0.013493850

-1.869864114

29

302.15

0.003309614

10.21

1.021E-08

0.014174096

-1.848504637

30

303.15

0.003298697

3.52

3.520E-09

0.004886662

-2.310987715

No statistical analysis is given due to the nature of the plot.

Run 2 -Graph of Log10Vapour Pressure vs Reciprocal Temperature see Attachment 3 Run 1 to 4.

Run 3

Temperature (ºC)

Temperature (K)

Reciprocal Temperature (K-1)

Mass Difference (µg)

Mass Difference (kg)

Vapour Pressure (Pa)

Log10Vp

20

293.15

0.003411223

4.68

4.680E-09

0.006497039

-2.187284526

21

294.15

0.003399626

5.37

5.370E-09

0.007454936

-2.127556093

22

295.15

0.003388108

0.07

7.000E-11

0.000097178

-4.012432339

24

297.15

0.003365304

4.86

4.860E-09

0.006746925

-2.170894109

25

298.15

0.003354016

7.11

7.110E-09

0.009870502

-2.005660778

26

299.15

0.003342805

0.10

1.000E-10

0.000138826

-3.857530379

27

300.15

0.003331667

9.83

9.830E-09

0.013646558

-1.864976861

28

301.15

0.003320604

11.00

1.100E-08

0.015270818

-1.816137694

29

302.15

0.003309614

12.27

1.227E-08

0.017033904

-1.768685816

30

303.15

0.003298697

13.25

1.325E-08

0.018394395

-1.735314500

No statistical analysis is given due to the nature of the plot.

Run 3 -Graph of Log10Vapour Pressure vs Reciprocal Temperature see Attachment 3 Run 1 to 4.

Run 4

Temperature (ºC)

Temperature (K)

Reciprocal Temperature (K-1)

Mass Difference (µg)

Mass Difference (kg)

Vapour Pressure (Pa)

Log10Vp

20

293.15

0.003411223

4.88

4.880E-09

0.006774690

-2.169110557

21

294.15

0.003399626

3.63

3.630E-09

0.005039370

-2.297623754

22

295.15

0.003388108

4.89

4.890E-09

0.006788573

-2.168221520

23

296.15

0.003376667

1.69

1.690E-09

0.002346153

-2.629643674

24

297.15

0.003365304

6.45

6.450E-09

0.008954252

-2.047970664

25

298.15

0.003354016

1.32

1.320E-09

0.001832498

-2.736956448

26

299.15

0.003342805

2.18

2.180E-09

0.003026399

-2.519073885

27

300.15

0.003331667

6.87

6.870E-09

0.009537320

-2.020573642

28

301.15

0.003320604

4.92

4.920E-09

0.006830220

-2.165565276

29

302.15

0.003309614

1.80

1.800E-09

0.002498861

-2.602257874

30

303.15

0.003298697

0.97

9.700E-10

0.001346609

-2.870758644

No statistical analysis is given due to the nature of the plot.

Run 1 -Graph of Log10Vapour Pressure vs Reciprocal Temperature see Attachment 3 Run 1 to 4.




Applicant's summary and conclusion

Conclusions:
The vapour pressure of the test item has been determined to be less than 9.4 x 10-3 Pa at 25ºC.
Executive summary:

INTRODUCTION

The vapour pressure of the test item has been determined.

Method employed is designed to be compatible with that specified in the current OECD Guidelines for Testing of Chemicals.

Method

The vapour pressure was determined using a vapour pressure balance with measurements being made at several temperatures and linear regression analysis used to calculate the vapour pressure at 25°C. Testing was conducted using a procedure designed to be compatible with Method 104 specified in the OECD Guidelines for Testing of Chemicals,23 March 2006.

Conclusion

The vapour pressure of the test item has been determined to be less than 9.4 x 10-3 Pa at 25ºC.