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EC number: 217-370-6 | CAS number: 1825-62-3
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 22-Mar-2005 to 22-Apr-2005
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- BAYERISCHES LANDESAMT FUR ARBEITSSCHUTZ, ARBEITSMEDIZIN UND SICHERHEITSTECHNIK
- Type of method:
- flask method
- Water solubility:
- 0.995 g/L
- Temp.:
- 20 °C
- Conclusions:
- Interpretation of results: moderately soluble (100-1000 mg/L)
A water solubility of 0.995 g/l at 24°C was determined in a reliable study conducted according to an appropriate test protocol, and in compliance with GLP.
Reference
Results
Method 1: EC test guideline A.6 / 1.6.2 Preliminary test
total amount of test substance [g] |
total amount of distilled water [g] |
stirring time [h] |
clear solution (yes/no) |
approximate solubility [g/l] |
2.0112 |
100 |
24 |
no |
< 20 |
1.7602 |
100 |
24 |
no |
< 18 |
1.5152 |
100 |
24 |
no |
< 15 |
1.2515 |
100 |
24 |
no |
< 12 |
1.0157 |
100 |
24 |
no |
< 10 |
0.7515 |
100 |
24 |
no |
< 8 |
0.5046 |
100 |
24 |
no |
< 6 |
0.2569 |
100 |
24 |
no |
< 3 |
0.1089 |
100 |
24 |
no |
1 |
Water solubility is approximately 1 – 3 g/l
Method 2:EC test guideline A.6 / 1.4.2. Flask method
Results: |
Preincubation time [h] |
Time at test temperature until measurement [h] |
Concentration [g/l]1) |
pH-value |
Vessel 1 |
24 |
24 |
1.000 |
7.0 |
Vessel 2 |
48 |
24 |
0.985 |
6.9 |
Vessel 3 |
72 |
24 |
1.000 |
7.0 |
1)mean values from 2 measurements; 1 w% = 0.1 g/l
Mean value of all three measurements: 0.995 g/l
Standard deviation: 0.009 g/l
Water solubility: 0.995 g/l
Annex
Results from1H NMR
sample ID |
sample name |
amount of the sample [g] |
amount of the internal standard [g] |
Integral of Silanol M3 |
Integral of the internal standard |
Silanol M3 [w%] |
378136 |
BW 1/24h1) |
1.1116 |
0.0474 |
0 |
100.0000 |
0 |
378137 |
Probe 1.1/24h |
0.9787 |
0.0489 |
11.1166 |
100.0000 |
0.095 |
378138 |
Probe 1.2/24h |
0.9932 |
0.0508 |
11.4323 |
100.0000 |
0.100 |
378139 |
BW 2/48h1) |
1.0440 |
0.0521 |
0 |
100.0000 |
0 |
378140 |
Probe 2.1/48h |
1.0274 |
0.0533 |
11.2032 |
100.0000 |
0.099 |
378141 |
Probe 2.2/48h |
1.0963 |
0.0492 |
12.7292 |
100.0000 |
0.098 |
378142 |
BW 3/72h1) |
1.0836 |
0.0486 |
0 |
100.0000 |
0 |
378143 |
Probe 3.1/72h |
1.1318 |
0.0497 |
12.9594 |
100.0000 |
0.097 |
378144 |
Probe 3.2/72h |
0.9806 |
0.0562 |
10.5220 |
100.0000 |
0.103 |
1) BW means blank
Description of key information
Trimethylsilanol: 995 mg/l at 20°C (flask method, OECD 105)
Key value for chemical safety assessment
- Water solubility:
- 995 mg/L
- at the temperature of:
- 20 °C
Additional information
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