Registration Dossier
Registration Dossier
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EC number: 940-875-4 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The 48-h acute toxicity of the test item to Daphnia magna was studied under semi-static conditions in a GLP study performed according to OECD TG 202 and EC Method C.2. The 48-h EC50 was > 100 mg/L and the NOEC was 100 mg/L, based on nominal concentrations.
Key value for chemical safety assessment
Additional information
One study is available. In this study, performed under GLP according to OECD TG 202 and EC Method C.2, twenty daphnids (4 replicates of 5 animals) were exposed to an aqueous dispersion of the test item at concentrations of 1.0, 3.2, 10, 32 and 100 mg/L for 48 hours at a temperature of approximately 21 °C under semi-static test conditions. The numbers of immobilized Daphnia were recorded after 24 and 48 hours. Analysis of the freshly prepared 100 mg/L media at 0 and 24 hours showed measured concentrations of 92 and 91 mg/L respectively. Analysis of the old or expired media at 24 and 48 hours for the 100 mg/L test preparation showed measured concentrations of 90 and 91 mg/L respectively. As near nominal concentrations were obtained it was considered justifiable to base the results on nominal concentrations only. Exposure of Daphnia magna to the test item gave EC50 values of greater than 100 mg/L. The No Observed Effect Concentration was 100 mg/L.
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