Registration Dossier
Registration Dossier
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EC number: 215-158-8 | CAS number: 1308-14-1
Toxicity to microorganisms
Administrative data
- Endpoint:
- toxicity to microorganisms
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Study period:
- 1995
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Information from a peer reviewed Assessment Report.Chromium(III) hydroxide is insoluble between pH 6.8 and 11 (see section 4.8). Under conditions < pH 6.8 hydrolysis takes place and at > pH11.5 hydroxocomplexes are formed. The main toxic principle of these solutions < pH6.8 and > pH11.5 is dissolved Cr(III). Therefore Chromium(III) chloride is used as supporting substance.
Data source
Reference
- Reference Type:
- other: Peer reviewed assessment report
- Title:
- Unnamed
- Year:
- 2 009
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Principles of method if other than guideline:
- data from peer-reviewed assessment report
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Chromium trichloride
- EC Number:
- 233-038-3
- EC Name:
- Chromium trichloride
- Cas Number:
- 10025-73-7
- Reference substance name:
- Chromium(III)chloride
- IUPAC Name:
- Chromium(III)chloride
Constituent 1
Constituent 2
Test organisms
- Test organisms (species):
- Tetrahymena pyriformis
- Details on inoculum:
- protozoan
Study design
- Test type:
- not specified
- Water media type:
- freshwater
Results and discussion
Effect concentrations
- Duration:
- 9 h
- Dose descriptor:
- IC50
- Effect conc.:
- 50 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- other: mg chromium/L
- Basis for effect:
- growth inhibition
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- The 9h growth inhibition of chromium(III)chloride to the Protozoan (Tetrahymena pyriformis) is IC50 = 50 mg chromium/L in freshwater.
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