Registration Dossier
Registration Dossier
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EC number: 212-053-9 | CAS number: 756-80-9
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vitro / ex vivo
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1986
- Reliability:
- 4 (not assignable)
Data source
Reference
- Reference Type:
- publication
- Title:
- Registry of Toxic Effects of Chemical Substances
- Author:
- Canadian Centre for Occupotional Health and Safety
- Year:
- 1 986
- Bibliographic source:
- RTECS
- Report date:
- 2001
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Standard Draize test.
Route of exposure: Administration onto the skin.
20 mg/24h.
Reaktion: Moderate - GLP compliance:
- no
Test material
- Reference substance name:
- O,O-dimethyl hydrogen dithiophosphate
- EC Number:
- 212-053-9
- EC Name:
- O,O-dimethyl hydrogen dithiophosphate
- Cas Number:
- 756-80-9
- Molecular formula:
- C2H7O2PS2
- IUPAC Name:
- O,O-dimethyl hydrogen dithiophosphate
Constituent 1
Test animals
- Species:
- rabbit
Test system
- Type of coverage:
- not specified
- Preparation of test site:
- not specified
- Vehicle:
- not specified
- Amount / concentration applied:
- 20 mg
- Duration of treatment / exposure:
- 24 h
Results and discussion
In vivo
- Irritant / corrosive response data:
- 0,0-dimethyl hyddrogen dithiophosphate was administated onto skin of rabbit. The dose was 20 mg and the exposure time 24h.
The result is recognized as beeing moderate skin irritating - Other effects:
- None
Any other information on results incl. tables
No other information
Applicant's summary and conclusion
- Interpretation of results:
- moderately irritating
- Remarks:
- Migrated information
- Conclusions:
- MP-1 is considered skin irritating
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