Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 231-912-9 | CAS number: 7778-74-7
Additional ecotoxological information
Administrative data
- Endpoint:
- additional ecotoxicological information
- Type of information:
- other: Literature review
- Adequacy of study:
- key study
- Study period:
- 09/04/2013
- Reliability:
- other: Not applicable
Data source
Reference
- Reference Type:
- other: Literature review
- Title:
- Unnamed
- Year:
- 2 013
- Report date:
- 2013
Materials and methods
Test material
- Reference substance name:
- Potassium perchlorate
- EC Number:
- 231-912-9
- EC Name:
- Potassium perchlorate
- Cas Number:
- 7778-74-7
- Molecular formula:
- ClHO4.K
- IUPAC Name:
- potassium perchlorate
- Test material form:
- not specified
Constituent 1
Results and discussion
Any other information on results incl. tables
For the purposes of the review potassium was not considered relevant, as potassium is a common element with well described environmental properties. As such, the perchlorate ion was focused on for the purposes of the review.
A number of conclusions can be drawn from the public domain information on the effects of perchlorate:
1) Perchlorate is a known contaminant of groundwater and drinking water
2) The perchlorate anion persists in groundwater, and its mobility in surface or ground water is so high that perchlorate essentially moves with the flow of water (diffusion and convection controlled movement)
3) The publication by Dean et al. 2003 recommends water-quality criterion maximum concentrations of 20 mg/L and a continuous concentration of 9.3 mg/L however, when compared to the aquatic species tests and summaries reviewed the concentrations recommended by Dean et al would induce sub-lethal effects during chronic exposure, it is recommended based on the reviewed public domain data that environmental concentrations of perchlorate should be <11 μg/L to ensure that sub-lethal effects are not occuring in aquatic species
4) Perchlorate is known to impair the functioning of the thyroid gland not only in humans but also wildlife (mammals, fish and amphibians). The thyroid gland regulates hormones within a narrow and specific concentration range. Impairment of the thyroid can (i) effect the development of the central nervous system of the foetus and infants (ii) affect skeletal growth and development (iii) affect metabolic activity and many organ systems.
5) Due to the interaction with the thyroid gland it is suspected that vertebrate species such as fish and amphibians will be the most sensitive aquatic species
For further information on the public domain information retrieved please see attached full review.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
