Registration Dossier
Registration Dossier
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EC number: 601-147-9 | CAS number: 111988-49-9
Endpoint summary
Administrative data
Description of key information
Additional information
The main abiotic pathway for degradation of the target compound (Z)-3-(6-chloro-3-pyridylmethyl)-1,3-thiazolidin-2-ylidenecyanamide is photodegradation in soil with a half-life of 18.8 days, while hydrolysis is no relevant degradation pathway of the substance (DT50 = > 1 year at 12 °C and pH5, pH 7 or pH 9).
A study on the ready biodegradability of the substance is not available. Biodegradation of the substance was investigated in a simulation study with different water/sediment systems. The substance was rapidly transferred from water to sediment, half-lives of the target compound at 20 °C ranged from 12.1 to 20.3 days (25.7 to 43.1 days, recalculated to 12 °C) under aerobic conditions and > 1 year under anaerobic conditions. After an incubation period of 100 days 14CO2 accounted for <5% of the initially applied radioactivity.
In a simulation study on the biodegradation of the test compound in natural pond water the DT50 was determined to be 274 days at 12 °C (recalculated from experimental data at 20 °C). After 62 days of incubation, radioactive carbon dioxide did not exceed 0.9% of the applied radioactivity.
In soil, the target substance attained 6.5 to 33.6% degradation (elevation of 14CO2) after 100 days and 20 °C, and the half-life of the test substance in soil was found to range from 0.7 to 4.7 days (1.5 to 10 days, recalculated to 12 °C).
The log Koc value of 2.94 indicates a low potential of the substance for adsorption to soil and sediment particles.
The determined water solubility of the substance is 0.159 g/L at 20 °C (OECD 105). Volatilasation from the water phase is not expected based on a Henry's Law Constant of 4.8xE-10 Pa m³/mol. The low log Kow (<= 3) of the substance indicates a low potential for bioaccumulation.
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