Registration Dossier
Registration Dossier
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EC number: 224-169-7 | CAS number: 4223-03-4
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The biodegradation potential of the substance has been assessed in Closed Bottle tests according to OECD 301D (non-GLP and therefore reliability 2). The best results obtained showed 35% biodegradation after 56 days. The results indicate that this substance is partially degradable under the test conditions and thus not readily biodegradable.
Key value for chemical safety assessment
Additional information
A number of tests were carried out under different conditions to determine the optimal conditions in the (prolonged) Closed Bottle test to obtain a ≥60% biodegradation result for N-tert-octylacrylamide. The Closed Bottle tests were performed according to OECD Test Guidelines (OECD, 1992).
Use of river water resulted in better biodegradability results compared to the use of activated sludge. Both
silica gel and humic acid did not improve the biodegradability with river water as inoculum. Surprisingly, the biodegradability in the presence of humic acid was even less (only the acrylic acid probably degraded). The best results obtained showed 35% biodegradation after 56 days.Biodegradation of only 35% indicates that the test substance is only partially biodegraded. The branching of the tert-octyl chain of N-tert-octylacrylamide is probably the major reason for the recalcitrance to biodegradation in the test and the environment. Products formed upon hydrolysis i.e. acrylic acid and some isomers of tert-octylamine are probably biodegradable.
In conclusion, the best results can be obtained with river water as inoculum. These results strongly indicate that this substance is partially degradable and thus not readily biodegradable.
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