Registration Dossier
Registration Dossier
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EC number: 224-169-7 | CAS number: 4223-03-4
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
N-(1,1,3,3 -tetramethylbutyl)acrylamide does not meet the criteria for B/vB and T based on criteria laid down in Annex XIII of REACH.
Persistence assessment
The best results in two ready biodegradability tests (OECD 301B and 301D) showed biodegradation percentages of approximately 30% at the end of the tests, strongly indicating that the test substance is only partially biodegraded. The branching of the tert-octyl chain of N-tert-octylacrylamide is probably the major reason for the recalcitrance to biodegradation in the test. Hydrolysis products, i.e. acrylic acid and some isomers of tert-octylamine are probably biodegradable. Thus the first reaction step (hydrolysis, possibly micro-organism mediated) is the rate-limiting step.
Based on the screening criteria the substance considered as potentially P (or vP).
Bioaccumulation assessment
As the log Kow of the test substance (2.25) is far below the screening cut-off level for 'B' (log Kow = 4.5), the substance is not considered to be B (or vB).
Toxicity assessment
The test substance does not meet the criteria for being Toxic (lowest NOEC is >0.1 mg/l; not classified for human toxicity endpoints), the substance is not considered to be 'T'.
- Likely routes of exposure:
As N-(1,1,3,3 -tetramethylbytul)acrylamide is not considered as a PBT or vPvB substance, the likely routes of exposure are not further assessed.
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