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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Epidemiological data

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Administrative data

Endpoint:
epidemiological data
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Title:
Health hazard evaluation report|No 78-90-739 FMC Corp. Specialty chemicals division, Nitro,|West Virginia
Author:
Tharr DG & Singal M
Year:
1980
Bibliographic source:
US Dep. of health and human services - Centers|for disease control - National institute for occupational|safety and health, Cincinnati, Ohio, Sept. 1980

Materials and methods

Study type:
case control study (retrospective)
Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
Epidemiological investigation of respiratory function
GLP compliance:
no
Remarks:
: not relevant

Test material

Constituent 1
Chemical structure
Reference substance name:
Phosphorus trichloride
EC Number:
231-749-3
EC Name:
Phosphorus trichloride
Cas Number:
7719-12-2
Molecular formula:
Cl3P
IUPAC Name:
phosphorus trichloride

Method

Exposure assessment:
measured

Results and discussion

Any other information on results incl. tables

Exposed employees had a significantly higher prevalence (65%) of occasional respiratory discomfort than unexposed employees (5%). No consistent association between pulmonary function parameters and exposure could be documented.

Applicant's summary and conclusion

Conclusions:
The authors conclude that intermittent exposure to PCl3 may cause respiratory symptoms but no effects on pulmonary function.
Executive summary:

Exposed and unexposed workers were examined by questionnaire and lung function test. The authors conclude that intermittent exposure to PCl3 may cause respiratory symptoms but no effects on pulmonary function.