Registration Dossier
Registration Dossier
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EC number: 700-680-5 | CAS number: -
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Based on the results of the present study Isostearic acid, esters with methyl α-D-glucoside showed no significant inhibitory effect of the test item at 100 mg/l; the deviations from the untreated controls were less than 15 %. The EC50 could not be calculated because Isostearic acid, esters with methyl α-D-glucoside proved to be non-toxic. Therefore the 3 h EC50 value based on inhibition of respiration was > 100 mg/L. The value is supported by the 1 h EC 50 data from Stearic acid, esters with methyl α-D-glucoside, Pseudomonas putida Bacteria Respiration test (DIN 38412 part 27) with a value > 10000 mg/l.
Key value for chemical safety assessment
Additional information
In a 3 hour toxicity study conducted according to OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test) and EU Method C.11 (Biodegradation: Activated Sludge Respiration Inhibition Test), the cultures of activated sludge of a predominantly domestic sewage treatment plant were exposed to Isostearic acid, esters with methyl α-D-glucoside at a nominal concentration of 100 mg/L under static conditions. No analytical control was performed.
There was no significant inhibitory effect of the test item at 100 mg/l; the deviations from the untreated controls were less than 15 %. The EC50 could not be calculated because Isostearic acid, esters with methyl α-D-glucoside proved to be non-toxic. Therefore the 3 h EC50 value based on inhibition of respiration was > 100 mg/L.
The value is supported by the 1 h EC 50 data from Stearic acid, esters with methyl α-D-glucoside. According to DIN 38412 part 27 (Bacteria Respiration test, preliminary draft) Pseudomonas putida was assessed by measuring the respiration rate after 1 hour at 0 and 10000 mg/l (nominal). No analytical control was performed. The 1 h EC 50 was higher than 10000 mg/l.
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