Isostearic acid, esters with methyl α-D-glucoside

Toxicity to aquatic algae and cyanobacteria

Description of key information

Based on the results of the present study with Pseudokirchnerella subcapitata only slight effects of the growth rate (8.5 % reduction in comparison to control) and yield (36 % reduction in comparison to control) were recorded at the maximum input  concentration of the test substance Isostearic acid, esters with methyl α-D-glucoside in test medium of 100 mg/L. The input concentration is above the solubility limit of the test substance. Therefore the 72 h ErC50 was > 100 mg/l (nominal).

Additional information

In a 72h acute toxicity study according to OECD guideline 201, the cultures of Pseudokirchnerella subcapitata NIVA CHL 1 were exposed to Isostearic acid, esters with methyl α-D-glucoside at nominal concentration of 100 mg/L under static conditions in accordance to OECD Guideline 201. No analytical control was performed, and the test substance could not be completely dissolved in test medium at the loading rate tested.

The NOEC value was 100 mg/L which was the maximum input concentration of the test substance.

72h-ErC50 for growth inhibition rate and the 72h-EyC50 for yield inhibition exceeded the maximum input concentration of 100 mg/L of the test substance. The % growth inhibition in the treated algal culture compared to the control was slightly reduced (8.5%). The reduction was not considered to be of biological significance, as it was less than 10%. The total yield was inhibited by 36% when compared to the control. Hence, a 50% effect level could not be reached at the maximum input concentration of the test substance.

There were no abnormalities noted.

 

Results Synopsis :

Test Organism: Pseudokirchnerella subcapitata NIVA CHL 1

Test Type: static

72 hr ErC₅₀for growth rate: >100mg/L  (nominal)

72 hr EyC₅₀for yield: >100mg/L (nominal)

72 hr NOEC for growth rate: 100mg/L (nominal)