Registration Dossier
Registration Dossier
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EC number: 944-574-9 | CAS number: -
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
The test item has been shown to be readily biodegradable and determination of hydrolysis as a function of pH is not relevant.
Key value for chemical safety assessment
Additional information
Testing was not carried out using Method 111 of the OECD Guidelines for Testing of Chemicals (13 April 2004) and Method C.7 Abiotic Degradation, Hydrolysis as a Function of pH of Commission Regulation (EC) No 440/2008 of 30 May 2008 for the following reasons. The test item as a whole was expected to be essentially insoluble in water. Therefore the test solution concentration required to dissolve all the components (less than half the water solubility) would be impractically low and a sufficiently sensitive analytical method was not available. The test item is a complex mixture, to which the test method is not ideally suited because each component that is unstable is likely to have its own hydrolytic rate. The main functional group within the components of the test item was a phosphite ester and, although phosphite esters will hydrolyse in both acidic and alkaline conditions, the test item components may have a significantly reduced hydrolytic rate due to them being essentially insoluble in water. Furthermore, the test item as a whole was determined to be readily biodegradable and in accordance with REACH Annex VIII, Section 9.2.1, Column 2, it is not necessary to investigate hydrolysis as a function of pH.
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