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EC number: 220-020-5
CAS number: 2605-79-0
1: Summarised results
2000 mg/kg b.w.
Within 24 h
Within 14 d
Mean body weight (g)
After 7 days
After 14 days
317.4 (+24.3 %)
370 (+44.9 %)
235.4 (+8.8 %)
256.0 (+18.3 %)
Inhibition of body weight gain
OECD Guideline 402 and EC Method B3
Method and material
C10 AO was applied to the shaved backs of CD rats (5 male/5 female) at a
dose of 2000 mg AO/kg bw. An occlusive bandage was applied and the rats
exposed for a period of 24 hours. After exposure the bandage was removed
and the rats observed for 14 days for mortality, clinical signs and skin
reactions. At the end of the study all animals were necropsied and
There were no deaths and no clinical signs of toxicity. No skin
reactions were observed in any of the animals and there were no
macroscopic findings at necropsy. Bodyweight gain was normal.
The acute dermal LD50 is > 2000 mg AO/kg bw.
In accordance with CLP Regulation (EC) No 1272/2008 the substance is not
classified for acute dernal toxicity.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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