Registration Dossier
Registration Dossier
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EC number: 236-690-7 | CAS number: 13464-97-6
Dermal absorption
Administrative data
- Endpoint:
- dermal absorption
- Type of information:
- other: assessment derived from available information
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: This is an assessmnet of the available information only.
- Justification for data waiving:
- other:
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
- Executive summary:
The rate and extent of absorption cannot be elucidated from the data available. Hydrazine mono-nitrate is classifiable as a skin sensitiser. Therefore, some absorption must occur to induce sensitisation. It is likely that the skin barrier will be compromised by the irritation/sensitisation observed following application of hydrazine mono-nitrate, and that some absorption via this route will occur. No data are available on exposure via inhalation. A default of 100% has been calculated, due to the irritant properties of hydrazine mono-nitrate.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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