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EC number: 949-219-1
CAS number: -
Table 1: Individual Clinical
Observations and Mortality Data
Animal No. and Sex
Effect Noted After Dosing
Effects Noted During Period After Dosing
0 = no signs of systemic toxicity
Table 2: Individual Body
Weights and Body Weight Changes
Animal Numberand Sex
Body Weight (g) at Day
Body Weight Gain (g) During Week
3: Individual Necropsy Findings
Time of Death
Killed Day 14
No abnormalities detected
The acute oral toxicity of the Reaction
mass of (4R)-4-(2-methoxypropan-2-yl)-1-methylcyclohexene and
cis-1-methoxy-4-(2-methoxypropan-2-yl)-1-methylcyclohexane in the Wistar
strain rat was investigated using the fixed dose method (OECD 420). Following
a sighting test at a dose level of 2000 mg/kg, an additional four fasted
female animals were given a single oral dose of test item at a dose
level of 2000 mg/kg body weight. Clinical
signs and body weight development were monitored during the study. All
animals were subjected to gross necropsy.
study condition the acute oral median lethal dose (LD50) of
the test item in the female Wistar strain rat was estimated to be
greater than 2000 mg/kg body weight (Globally Harmonized Classification
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