Registration Dossier
Registration Dossier
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EC number: 203-026-2 | CAS number: 102-36-3
Flash point
Administrative data
Link to relevant study record(s)
- Endpoint:
- flash point, other
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- no data
- GLP compliance:
- not specified
- Type of method:
- closed cup
- Specific details on test material used for the study:
- purity not specified
- Flash point:
- 142.15 °C
- Remarks on result:
- other: The corresponding atmospheric pressure was not reported.
- Executive summary:
Daubert, T.E. et. al, 1989
The flash point (closed cup method) of 3,4-dichlorophenyl isocyanate is 142.15 °C. The corresponding atmospheric pressure was not reported.
- Endpoint:
- flash point, other
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- no data
- GLP compliance:
- not specified
- Type of method:
- closed cup
- Specific details on test material used for the study:
- purity not specified
- Key result
- Flash point:
- 123 °C
- Remarks on result:
- other: The corresponding atmospheric pressure was not reported.
- Executive summary:
Chemsafe, 2008
The flash point (closed cup method) for 3,4-dichlorophenyl isocyanate is 123°C. The corresponding atmospheric pressure was not reported.
Referenceopen allclose all
Pressure not reported
Pressure not reported
Description of key information
The individual study reports (data from handbooks or collection of data) show some deficiencies with respect to the comprehensiveness of the experimental details. Therefore, a reliability of 1 or 2 and thus adequacy as key study was not assignable for any of the individual studies. Consequently, the studies were assigned a Klimisch score of 4 (according to guidance document R.4, ‘not assignable: studies or data […] which are only listed in short abstracts or secondary literature (books, reviews, etc.)). As the individual studies report values are in a similar range, collectively, these studies can be used to conclude on this endpoint and to satisfy the information requirement.
The flash point of 3,4-dichlorophenyl isocyanate was determined in two individual experimental studies and found to be in the range of 123 - 142.15 °C:
Chemsafe, 2008
The flash point (closed cup method) for 3,4-dichlorophenyl isocyanate is 123°C. The corresponding atmospheric pressure was not reported.
Daubert, T.E. et. al, 1989
The flash point (closed cup method) of 3,4-dichlorophenyl isocyanate is 142.15 °C. The corresponding atmospheric pressure was not reported.
The reported flash point of 123 °C (lowest value, Chemsafe, 2008) was chosen as the key value for chemical safety assessment.
Key value for chemical safety assessment
- Flash point at 101 325 Pa:
- 123 °C
Additional information
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