Registration Dossier
Registration Dossier
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EC number: 226-501-6 | CAS number: 5413-60-5
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- RTECS Number : PC1210000
- Author:
- RTECS Database
- Year:
- 2 012
- Bibliographic source:
- RTECS (Registry of Toxic Effects of Chemical Substances) :Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 46,S1,2008
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Standard Draize test
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate
- EC Number:
- 226-501-6
- EC Name:
- 3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate
- Cas Number:
- 5413-60-5
- Molecular formula:
- C12H16O2
- IUPAC Name:
- 3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate
- Test material form:
- gas under pressure: refrigerated liquefied gas
- Details on test material:
- - Name of test material (as cited in study report): 3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate
- Substance type: Organic
- Physical state: Liquid
Constituent 1
Test animals / tissue source
- Species:
- rabbit
- Strain:
- not specified
Test system
- Vehicle:
- not specified
- Controls:
- not specified
Results and discussion
In vivo
Results
- Irritation parameter:
- overall irritation score
- Basis:
- mean
- Reversibility:
- not specified
- Remarks on result:
- other: Dose data : 6.25% , Moderately irritating
Applicant's summary and conclusion
- Interpretation of results:
- moderately irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- 3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate is moderately irritating to rabbit eye at dose conc. of 6.25% .
- Executive summary:
3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate is moderately irritating to rabbit eye at dose conc. of 6.25% .
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