Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Secondary information taken from OECD SIDS document. Original report given as of high quality, but not available for review.

Data source

Reference
Reference Type:
secondary source
Title:
No information
Author:
OECD
Bibliographic source:
Initial Targeting Assessment Report For SIAM 31 Paris, France, 19-22 October 2010

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 401 (Acute Oral Toxicity)
GLP compliance:
yes
Test type:
acute toxic class method
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
Sodium hydrogen 4-amino-5-hydroxynaphthalene-2,7-disulphonate
EC Number:
226-736-4
EC Name:
Sodium hydrogen 4-amino-5-hydroxynaphthalene-2,7-disulphonate
Cas Number:
5460-09-3
Molecular formula:
C10H9NO7S2.Na
IUPAC Name:
sodium hydrogen 4-amino-5-hydroxynaphthalene-2,7-disulfonate
Details on test material:
purity: 87.4 %

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: gavage

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
>= 2 000 mg/kg bw
Mortality:
none
Clinical signs:
other: no effects
Gross pathology:
no effects

Applicant's summary and conclusion

Interpretation of results:
practically nontoxic
Remarks:
Migrated information Criteria used for interpretation of results: EU