Registration Dossier
Registration Dossier
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EC number: 617-903-6 | CAS number: 86675-46-9
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The 96-h ErC50 value of >1,000 mg/L and the 96-h NOErC of 500 mg/L in the freshwater alga Pseudokirchneriella subcapitata are used in the assessment.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 1 000 mg/L
- EC10 or NOEC for freshwater algae:
- 500 mg/L
Additional information
A GLP-compliant OECD 201 guideline study with Pseudokirchneriella subcapitata (tested as: Selenastrum capricornutum) is available forPolyol IXOL M125(Solvay Duphar B.V., 1992d). Algae were exposed to nominal concentrations ranging from 125 to 1,000 mg/L under static conditions for 96 hours. The test concentrations were analytically verified andwithin 80% of nominal concentrations. The results show that at 1,000 mg/L the inhibition is 3 %. At concentrations of 125, 250, 500 and 750 mg/L the growth rate is not inhibited. Although the inhibition to the growth rate by 750 and 1000 mg/L appeared statistically significant, these inhibitions (0 and 3%, respectively) were considered to be of no biological significance. The 96-h ErC50 value is >1,000 mg/L and the 96-h NOErC is 500 mg/L (both based on nominal concentrations).
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