2,3-epoxypropyl phenyl ether

Short-term toxicity to fish

Administrative data

Endpoint:

short-term toxicity to fish

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Scientific publication with restrictions compared to Guideline Study (limited documentation)

Data source

Reference

Reference Type:

publication

Title:

The acute toxicity of some Petrochemicals to Goldfish

Author:

Bridie AL, Wolff CJM, Winter M

Year:

1979

Bibliographic source:

Water Res.13(7): 623-626

Materials and methods

Principles of method if other than guideline:

Guideline released by American Public Health Association (ALPHA, 1971)

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

2,3-epoxypropyl phenyl ether

EC Number:

204-557-2

EC Name:

2,3-epoxypropyl phenyl ether

Cas Number:

122-60-1

Molecular formula:

C9H10O2

IUPAC Name:

2-(phenoxymethyl)oxirane

Details on test material:

NAME: 1-Phenoxy-2,3-epoxypropane
CAS: 122-60-1

Sampling and analysis

Analytical monitoring:

no

Test solutions

Details on test solutions:

Solutions of 25L were made in local tap-water.
The analysis was, in mg/L:
chloride=65,
nitrite =0,
nitrate=4,
sulfate=35,
phosphate= 0.15,
hydrogenecarbonate = 25,
silicate = 25,
ammonium = 0,
Fe2+ = 0.05,
Mn = 0,
Ca 2+ = 100,
Mg 2+ = 8,
alkali as Na+ = 30
and pH = 7.8.

Test organisms

Test organisms (species):

Carassius auratus

Details on test organisms:

- Common name: Goldfish
- Length at study initiation:(6.2 ± 0.7) cm
- Weight at study initiation: (3.3 ± 1.0) g

Study design

Test type:

static

Water media type:

freshwater

Limit test:

yes

Total exposure duration:

1 d

Test conditions

Hardness:

no data

Test temperature:

20± 1 °C

pH:

7.0

Dissolved oxygen:

> 4 mg/L

Salinity:

no data

Details on test conditions:

TEST SYSTEM
- Test vessel: glass tanks (42 cm x28 cm x28 cm)
- Fill volume: 25 l
- No. of organisms per vessel: 10
- No. of vessels per concentration (replicates): 1
- No. of vessels per control (replicates): 1

TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: local tap water

EFFECT PARAMETERS MEASURED (with observation intervals if applicable) :
Mortality after 24 and 96 hours

Reference substance (positive control):

no

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

24 h

Dose descriptor:

LC50

Effect conc.:

69 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Effect concentrations 2

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

43 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality (fish)