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EC number: 700-803-2 | CAS number: 14531-84-1
The sensitisation potential of Dienone was assessed using a method based on the maximisation test described by Magnusson and Kligman (1970). The study involved the treatment of guinea pigs using two procedures: the potential induction of an immune response and a challenge by assessing the degree of erythema.
Following challenge of previously induced guinea pigs with a 92% or a 75% w/v preparation of the test substance in corn oil, no erthematous response was seen on any of hte test or control animals. A positive control study using hexylcinnamaldehyde demonstrated the sensitivity of the test system.
Dienone is not a skin sensitiser under the conditions of the test.
By read across, delta-6 -nandrolone is also not a skin sensitiser under these conditions.
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