Registration Dossier
Registration Dossier
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EC number: 212-429-2 | CAS number: 816-19-3
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (invertebrates)= 23.8 mg/l (95% CL: 18.7-30.3 mg/l), 48 hour, freshwater, EPA OPPTS 850.1010, ABC Laboratories Inc. 2004
NOEC (invertebrates)= 18.7 mg/l, 48 hour, freshwater, EPA OPPTS 850.1010, ABC Laboratories Inc. 2004
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 23.8 mg/L
Additional information
The acute toxicity to Daphnia magna was carried out according to US. EPA OPTTS 850.1010 and OECD 202 Daphnia sp., Acute Immobilisation Test guidelines. The mean measured concentrations (average of the 0- and 48-hour measured concentrations) of test substance ranged from 2.06 to 30.3 mg a.i./L and from 57 to 75% of the nominal concentrations. All measured concentrations were corrected for the average QC sample recovery on that day. Water quality parameters remained within acceptable limits for Daphnia magna throughout the test. Based on mean measured concentrations of test substance, the 48-hour EC50 was 23.8 mg a.i./L (estimated 95% confidence limits: 18.7 and 30.3 mg a.i./L). The 48-hour NOEC was 18.7 mg a.i./L based on the absence of sublethal effects and immobility at this and all lower test concentrations.
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