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Ecotoxicological information

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The aquatic toxicity of lipase has been testet in species representing three trophic levels, i.e. algae, crustacaens and fish. All tests performed were short-term toxicity tests conducted according to OECD guidelines, and in compliance with GLP.

The no-observed-effect concentrations (NOEC) were observed to be the highest exposure concentrations in both fish and Daphnia and thus no LC50/EC50 values could be determined for these two aquatic organisms.

The most sensitive aquatic organism was green alga and thus the ErC50 value obtained in the algal growth inhibition assay was used for derivation of aquatic PNEC.

Following values were derived from the acute aquatic toxicity studies with lipase:

Short-term toxicity to fish:

NOEC = 11.2 mg active enzyme protein (aep)/L

Short-term toxicity to Daphnia magna:

NOEC 37.4 mg aep/L

Toxicity to aquatic algae:

NOEC = 7.4 mg aep/L

ErC50 = 18 mg aep/L

EbC50 = 17.6 mg aep/L