Registration Dossier

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Prediction model
Title:
Short-term toxicity to aquatic invertebrates by ECOSAR Version 1.10
Author:
ECOSAR Version 1.10
Year:
2012
Bibliographic source:
ECOSAR v1.1 Class-specific Estimations, Environmental Protection Agency (EPA) office of Chemical Safety and Pollution Prevention

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: Modeling database
Principles of method if other than guideline:
ECOSAR v1.1
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Details on test material:
- Name of test material: 2-aminobenzene-1, 4-disulphonic acid
- Molecular formula: C6H7NO6S2
- Molecular weight: 253.25
- Substance type: Organic

Sampling and analysis

Analytical monitoring:
not specified

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
Daphnia magna

Study design

Test type:
not specified
Water media type:
not specified
Total exposure duration:
48 h

Results and discussion

Effect concentrations
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
240.768 mg/L
Nominal / measured:
estimated
Conc. based on:
test mat.
Basis for effect:
mortality

Applicant's summary and conclusion

Conclusions:
Short term toxicity (48 h) value of 2-aminobenzene-1, 4-disulphonic acid to Daphnia magna is estimated to be LC50: 240.768 mg/L.
Executive summary:

Short term toxicity (48 h) value of 2-aminobenzene-1, 4-disulphonic acid to Daphnia magna is estimated to be LC50: 240.768 mg/L. This value indicates that 2-aminobenzene-1, 4-disulphonic acid is not toxic to Daphnia magna.