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Physical & Chemical properties

Water solubility

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Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2020-11-30 to 2020-12-04
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2021
Report date:
2021

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
1995
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Version / remarks:
2014
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
(5Z)-5-(phenylmethylidene)imidazolidine-2,4-dione
EC Number:
700-728-5
Cas Number:
74805-60-0
Molecular formula:
C10H8N2O2
IUPAC Name:
(5Z)-5-(phenylmethylidene)imidazolidine-2,4-dione
Test material form:
solid: particulate/powder

Results and discussion

Water solubilityopen allclose all
Key result
Water solubility:
82.4 mg/L
Conc. based on:
test mat.
Incubation duration:
24 h
Temp.:
20 °C
pH:
6.8
Water solubility:
91.6 mg/L
Conc. based on:
test mat.
Incubation duration:
48 h
Temp.:
20 °C
pH:
6.8
Water solubility:
95.1 mg/L
Conc. based on:
test mat.
Incubation duration:
72 h
Temp.:
20 °C
pH:
6.9

Any other information on results incl. tables

Water Solubility Results at 20°C for n-Butyltriphenylphosphonium bromide

Preincubation time

Replicat No.

Concentration [mg/L]

Mean [mg/L]

Measured pH

Tyndall-Effect

24 h

1

83.1

82.4

6.994

negative

2

81.8

6.775

negative

48 h

1

98.5

91.6

6.987

negative

2

84.6

6.600

negative

72 h

1

104.8

95.1

6.807

negative

2

85.3

6.920

negative

Mean (48 -72 h)

 

 

93.3

6.868

negative

Deviation [%] (24-72 h)

 

 

3.8

 

 

Applicant's summary and conclusion

Conclusions:
The water solubility of the test item is 93.3 mg/L (20°C, pH 6.9). The water solubility was determined according to OECD guideline 105 (1995) and Council Regulation (EC) No. 260/2014, Method A.6 using the flask method at 20 ± 0.5°C with pre-incubation at 30 ± 0.5°C.