2,4-Imidazolidinedione, 5-(phenylmethylene)-, (5Z)-

Water solubility

Administrative data

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2020-11-30 to 2020-12-04

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2021

Report date:

2021

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Version / remarks:

1995

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Version / remarks:

2014

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Test material

Test material information

Constituent 1

Reference substance name:

(5Z)-5-(phenylmethylidene)imidazolidine-2,4-dione

EC Number:

700-728-5

Cas Number:

74805-60-0

Molecular formula:

C10H8N2O2

IUPAC Name:

(5Z)-5-(phenylmethylidene)imidazolidine-2,4-dione

Test material form:

solid: particulate/powder

Results and discussion

Water solubility

Water solubility 1

Key result

Water solubility:

82.4 mg/L

Conc. based on:

test mat.

Incubation duration:

24 h

Temp.:

20 °C

pH:

6.8

Water solubility 2

Water solubility:

91.6 mg/L

Conc. based on:

test mat.

Incubation duration:

48 h

Temp.:

20 °C

pH:

6.8

Water solubility 3

Water solubility:

95.1 mg/L

Conc. based on:

test mat.

Incubation duration:

72 h

Temp.:

20 °C

pH:

6.9

Any other information on results incl. tables

Water Solubility Results at 20°C for n-Butyltriphenylphosphonium bromide

Preincubation time	Replicat No.	Concentration [mg/L]	Mean [mg/L]	Measured pH	Tyndall-Effect
24 h	1	83.1	82.4	6.994	negative
	2	81.8		6.775	negative
48 h	1	98.5	91.6	6.987	negative
	2	84.6		6.600	negative
72 h	1	104.8	95.1	6.807	negative
	2	85.3		6.920	negative
Mean (48 -72 h)			93.3	6.868	negative
Deviation [%] (24-72 h)			3.8

Applicant's summary and conclusion

Conclusions:

The water solubility of the test item is 93.3 mg/L (20°C, pH 6.9). The water solubility was determined according to OECD guideline 105 (1995) and Council Regulation (EC) No. 260/2014, Method A.6 using the flask method at 20 ± 0.5°C with pre-incubation at 30 ± 0.5°C.