Registration Dossier
Registration Dossier
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EC number: 203-187-9 | CAS number: 104-23-4
Endpoint summary
Administrative data
Description of key information
Bioaccumulation: aquatic/sediments:
Using BCFBAF Program (v3.00) model of EPI suite (2018) the estimated bio concentration factor (BCF) for test chemical is 3.162 L/kg wet-wt at 25 deg. c which does not exceed the bioconcentration threshold of 2000. Therefore it is concluded that test chemical is non-bioaccumulative in food chain.
Additional information
Bioaccumulation: aquatic/sediments:
Different studies have been reviewed for Bioaccumulation in aquatic organisms endpoint for test chemical and its read across chemicals and their results are summarized below.
In first study bio concentration factor (BCF) of test chemical was estimated by using BCFBAF Program (v3.00) model of EPI suite (2018) the estimated bio concentration factor (BCF) for test chemical was 3.162 L/kg wet-wt at 25 deg. c .
Next study was reviewed from authoritative database (HSDB) in this study the BCF value of test chemical estimated was 3.0 dimensionless by using a log Kow of 0.97 and a regression derived equation.
Another study was also reviewed from authoritative database (HSDB) in this study the BCF value of test chemical was estimated to be 30 dimensionless by using a measured water solubility and a recommended regression-derived equation.
By considering the results of all the studies mentioned above it is concluded that BCF value of test chemical is in range of 3.162 -30 dimensionless and this range BCF value is far less than 2000 criteria of CLP regulation. On the basis of this range BCF value it is concluded that test chemical is non-bioaccumulative.
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