Registration Dossier
Registration Dossier
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EC number: 203-187-9 | CAS number: 104-23-4
Endpoint summary
Administrative data
Description of key information
Hydrolysis
Various studies has been reviewed to determine the half-life of the test chemical. The studies are as mentioned below:
In first study, the hydrolysis rate constant of chemical obtained was 2.9X10+9 L/mol-sec L/mol/sec. The half-life of hydrolysis obtained at pH 7 was 276 days. Since half-life of hydrolysis is more than 10 days so it is concluded that test chemical shows negligible hydrolysis that means it is not hydrolysable.
In another study, the half-life of hydrolysis obtained at pH 2.96, 7, and 10.95 at 25 deg C was 11.11, 11, and 10.73 years. Since half-life of hydrolysis is more than 10 days so it is concluded that test chemical shows negligible hydrolysis. Thus it is concluded as not hydrolysable.
On the basis of the available experimental studies, it is concluded that test substance has negligible hydrolysis.
Additional information
Hydrolysis
Various studies have been reviewed to determine the half-life of the test chemical. The studies are as mentioned below:
In first study, the hydrolysis rate constant of chemical obtained was 2.9X10+9 L/mol-sec L/mol/sec. The half-life of hydrolysis obtained at pH 7 was 276 days. Since half-life of hydrolysis is more than 10 days so it is concluded that test chemical shows negligible hydrolysis that means it is not hydrolysable.
In another study, the half-life of hydrolysis obtained at pH 2.96, 7, and 10.95 at 25 deg C was 11.11, 11, and 10.73 year respectively. Since half-life of hydrolysis is more than 10 days so it is concluded that test chemical shows negligible hydrolysis. Thus it is concluded as not hydrolysable.
On the basis of the experimental studies of the test chemical and applying the weight of evidence approach, the hydrolysis half-life value of the test chemical can be expected to be 276 days at pH 7 and was 11.11, 11, and 10.73 year at pH 2.96, 7, and 10.95 respectively at 25 deg C. Thus, based on this half-life value, it can be concluded that the test chemical is not hydrolysable.
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