Registration Dossier

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Genetic toxicity in vitro

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (negative)

Genetic toxicity in vivo

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Experimental data on in vitro mutagenicity on bacteria are available to nearly all representatives of the category of Guerbet alcohols. All tests are negative. Studies on mammalian cells are only available for the C16 Guerbet alcohol (CAS-No. 2425-77-6). Both a cytogenetic assay (chromosome aberration test) as well as a gene mutation study (HPRT test) are negative. Due to the similar structure with no additional functional groups these data can be cross-read to the whole category of Guerbet alcohols.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

Avalaible data are conclusive but not sufficient for classification of 2 -octyldodecan-1-ol with regard to mutagenicity / genotoxicity.