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EC number: 219-370-1 | CAS number: 2425-77-6
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Repeated dose toxicity: via oral route - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- NOAEL
- 839.6 mg/kg bw/day
Repeated dose toxicity: inhalation - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: inhalation - local effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: dermal - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: dermal - local effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
A well documented 13 week subchronic toxicity study is available for the structurally related 2-octyldodecan-1-ol (C20). Male and female rats received the sustance daily by gavage. There were no indications that 2-octyldodecan-1-ol was toxic at the limit dose of 1 ml/kg bw/d. Due to their structural similarity no effects are expected after repeated oral application of the other Guerbet alcohols of this category either.
Additional data are available for the linear C22-alcohol docosan-1-ol. In a repeated dose toxicity study conducted according to a Guideline similar to OECD Guideline 408 male and female rats received oral doses of up to 1000 mg/kg daily for 26 weeks. No effects were observed resulting in a NOEL of 1000 mg/kg bw.
Justification for classification or non-classification
Available data are conclusive but not sufficient for classfication of 2 -hexyldecan-1 -ol with regard to repeated dose toxicity.
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