Bicyclo[3.1.1]hept-2-ene-2-ethanol, 6,6-dimethyl-, 2-acetate, (1R,5S)-

Viscosity

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

viscosity

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

January 2012

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Remarks:

Study performed according to international guidelines but not under GLP and with some lack of details.

Reason / purpose for cross-reference:

reference to other study

Reason / purpose for cross-reference:

reference to same study

Qualifier:

according to guideline

Guideline:

OECD Test Guideline 114 (Viscosity of Liquids)

Deviations:

not specified

GLP compliance:

no

Type of method:

capillary viscometer (static)

Key result

Temp.:

other: 25.0°C

Parameter:

kinematic viscosity (in mm²/s)

Value:

5.19

Three measurements were carried out at 25°C with the following results:

5.1892 mm²/s

5.1896 mm²/s

5.1898 mm²/s

Mean value: 5.1895 mm²/s

Conclusions:

The kinematic viscosity of nopyl acetate was determined to be 5.190 +/- 0.25 mm²/s at 25°C.

In accordance with Directive 67/548/EEC and CLP Regulation (EC) No 1272/2008, nopyl acetate does not meet the criteria for classification as an aspiration hazard. Although this substance is a low viscosity and mobile liquid, its chemical structure indicates a low potential for surface activity. In addition, there is no evidence of aspiration toxicity for this material from either human experience or from animal toxicity data and it is not a member of a recognized category of materials having aspiration toxicity potential.

Executive summary:

The determination of the kinematic viscosity was performed in accordance with OECD Guideline No 114.

The capillary viscometer was used.

Three measurements were performed at 25°C. The kinematic viscosity of nopyl acetate was determined to be 5.189 mm²/s.

Reference 2

Endpoint:

viscosity

Type of information:

experimental study

Adequacy of study:

key study

Study period:

January 2013

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Study performed according to international guidelines but not under GLP and with some lack of details.

Reason / purpose for cross-reference:

reference to other study

Reason / purpose for cross-reference:

reference to same study

Qualifier:

according to guideline

Guideline:

OECD Test Guideline 114 (Viscosity of Liquids)

Deviations:

not specified

GLP compliance:

no

Type of method:

rotational viscometer (dynamic)

Key result

Temp.:

20°C

Parameter:

dynamic viscosity (in mPa s)

Value:

7.7

Remarks on result:

other: shear rate = 583 s-1

Key result

Temp.:

40°C

Parameter:

dynamic viscosity (in mPa s)

Value:

5

Remarks on result:

other: shear rate = 583 s-1

Measured values at different shear rate

The results obtained at 20°C were the following:

Viscosities of the test item measured at 20°C:

Shear rate (1/s)	Viscosity (mPa.s)
349.4	8.2
583.1	7.7
971.6	7.1
1610	6.7

The results obtained at 40°C were the following:

Viscosities of the test item at 40°C:

Shear rate (1/s)	Viscosity (mPa.s)
349.4	5.5
583.1	5.0
971.6	4.5
1610	4.3

The viscosity was constant at all shear rates at both temperatures. The test item was thus considered to be a Newtonian fluid.

Measured values at a constant shear rate

Determination of the viscosity of the test item at a constant shear rate of 583.1 s^-1

Temperature	Viscosity (1st measurement)	Viscosity (2nd measurement)	Viscosity (3rd measurement)
20°C	7.6 mPa.s	7.7 mPa.s	7.7 mPa.s
40°C	5.0 mPa.s	5.0 mPa.s	5.0 mPa.s

Conclusions:

The dynamic viscosity of the test item at 20°C and 40°C ranged between 4.3 to 8.2 mPa.s at a shear rate from 349 to 1610 s-1.
The test item was considered to be a Newtonian fluid.

The dynamic viscosity of nopyl acetate was determined to be:
- 7.7 mPa.s at 20°C ± 0.2°C at constant shear rate of 583 s-1,
- 5.0 mPa.s at 40°C ± 0.1°C at constant shear rate of 583 s-1.

In accordance with Directive 67/548/EEC and CLP Regulation (EC) No 1272/2008, nopyl acetate does not meet the criteria for classification as an aspiration hazard. Although this substance is a low viscosity and mobile liquid, its chemical structure indicates a low potential for surface activity. In addition, there is no evidence of aspiration toxicity for this material from either human experience or from animal toxicity data and it is not a member of a recognized category of materials having aspiration toxicity potential.

Executive summary:

The determination of the viscosity was performed in accordance with OECD Guideline No 114 and with Analytical Method DRT 5230 “Determination of dynamic viscosity with a rotary viscometer Haake VT550 or Rheolab QC”.

 

The dynamic viscosity of the test item at 20°C and 40°C ranged between 4.3 to 8.2 mPa.s at shear rates from 349 to 1610 s^-1.

The test item was considered to be a Newtonian fluid.

The dynamic viscosity of nopyl acetate was determined to be:

- 7.7 mPa.s at 20.0°C ± 0.2°C at a constant shear rate of 583 s^-1,

- 5.0 mPa.s at 40°C ± 0.1°C at a constant shear rate of 583 s^-1.

Description of key information

The dynamic viscosity was determined with a rotational viscometer. 
The substance can be considered as a Newtonian fluid. 
The dynamic viscosity of nopyl acetate at a shear rate of 583 s-1 is 7.7 mPa.s at 20°C and 5.0 mPa.s at 40°C.
In accordance with Directive 67/548/EEC and CLP Regulation (EC) No 1272/2008, nopyl acetate does not meet the criteria for classification as an aspiration hazard. Although this substance is a low  viscosity and mobile liquid, its chemical structure indicates a low potential for surface activity. In addition, there is no evidence of aspiration toxicity for this material from either human experience or from animal toxicity data and it is not a member of a recognized category of materials having aspiration toxicity potential.

Key value for chemical safety assessment

Viscosity:

7.7 mPa · s (dynamic)

at the temperature of:

20 °C

Additional information

Key study conducted according to OECD 114 Guideline.

The result is scientifically acceptable but not obtained under GLP. Therefore a reliability of 2 (reliable with restrictions) was assigned.

A supporting study with a consistent result confirms the key study value.