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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

An acute aquatic toxicity study was performed on Daphnia magna in accordance with OECD Guideline No 202.
The 48h-EC50 of nopyl acetate for freshwater invertebrates is 11.95 mg/L.

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
11.95 mg/L

Additional information

Key study conducted according to OECD 202 and EU C2 Guidelines under GLP without deviation.

Daphnids were exposed to nopyl acetate at nominal concentrations of 5, 6.8, 9.1, 12.3, 16.7 and 22.5 mg/L. Immobilisation of daphnids was recorded in a semi-static 48-hour test by visual observation after 24 and 48 hours. The concentrations of the test substance were measured at the start of the study, at 24 h (new and old solutions) and at the end of the test. The concentrations were not satisfactorily maintained within ± 20% of the initial concentrations throughout the test, thus the EC50 were based on the geometric mean of the measured concentrations. The 48h-EC50 determined in this study can be used as key value for chemical safety assessment.