Registration Dossier
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EC number: 800-940-9 | CAS number: 35836-72-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
An acute aquatic toxicity study was performed on Daphnia magna in accordance with OECD Guideline No 202.
The 48h-EC50 of nopyl acetate for freshwater invertebrates is 11.95 mg/L.
Key value for chemical safety assessment
- EC50/LC50 for freshwater invertebrates:
- 11.95 mg/L
Additional information
Key study conducted according to OECD 202 and EU C2 Guidelines under GLP without deviation.
Daphnids were exposed to nopyl acetate at nominal concentrations of 5, 6.8, 9.1, 12.3, 16.7 and 22.5 mg/L. Immobilisation of daphnids was recorded in a semi-static 48-hour test by visual observation after 24 and 48 hours. The concentrations of the test substance were measured at the start of the study, at 24 h (new and old solutions) and at the end of the test. The concentrations were not satisfactorily maintained within ± 20% of the initial concentrations throughout the test, thus the EC50 were based on the geometric mean of the measured concentrations. The 48h-EC50 determined in this study can be used as key value for chemical safety assessment.
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