Registration Dossier
Registration Dossier
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EC number: 620-341-4 | CAS number: 61358-25-6
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (48 h) = 0.64 mg/L for Daphnia magna (OECD 202)
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.64 mg/L
Additional information
The short-term toxicity of PF-6 (CAS 61358-25-6) to aquatic invertebrates was investigated in a GLP guideline study. The static test was performed according to OECD 202 (Kimmel, 2012) with the water flea (Daphnia magna). Several dilutions (up to 1:320) of a filtrate with nominal 100 mg/L were tested in this study. The test substance was analyzed using HPLC/UV analysis. Duplicate samples were tested at the beginning and at the end of the test. The results from chemical analysis indicated that the substance remained stable during the test (97 - 100% of initially measured concentration).The biological results were related to the geometric mean of the measured concentrations of the test item. The EC50 was calculated to be 0.64 mg/L and the NOEC was determined at 0.30 mg/L based on the measured concentrations.
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