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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

An acute toxicity test with Zebrafish (Brachydanio rerio) was performed for 96 hours according to the OECD guideline.

The LC50,96h is >100 % v/v saturated solution or >100 mg loading rate of the test substance/L.

The LC10,96h is >100 % v/v saturated solution or >100 mg loading rate of the test substance/L.

An acute toxicity test with Daphnia magna was performed according to EC and OECD guidelines.

EC50,48h > 100 mg loading rate of the test substance/L.

EC10,48h > 100 mg loading rate of the test substance/L.

An acute growth inhibition test according to the EC-guideline was performed with Pseudokirchneriella subcapitata for 72 h.

ErC50,72h > 100.5 mg loading rate of the test substance/L.

ErC10,72h = 74.5 mg loading rate of the test substance/L.

A respiration inhibition test with activated sewage sludge was performed according to OECD-guideline.

EC50,3h value of >1000 mg/L. The NOEC after 3 hours exposure is 1000 mg/L.

The LC50/EC50 for fish, Daphnia and algae are >100 mg loading rate / L. This is in line with the estimated toxicity that could be caused by the low concentrations of Li of 0.45 to 1.2 mg Li/L test media, detected after prolonged stirring of the test substance at 100 mg loading rate/L. No extensive environmental transformation of the constituent metal elements was therefore observed, even with the very fine powder used. Titanium is even much less (compared to Li) or not at all transformed to a soluble species.

A comparison is made with the known toxicity of soluble Li-compounds to the 3 aquatic organisms, especially LiOH:

Fish: LC50,96h = 25.4 mg Li/L

Daphnia: EC50,48h = 7.8 mg Li/L, without pH-adjustment

Daphnia: EC50,48h = 14.0 mg Li/L, with pH-adjustment

Algae: EC50,72h = 35.7 mg/L

EC50/LC50 of the soluble LiCl (in mg Li/L), which could also be used for comparison, are higher for Daphnia (40.8 mg Li/L) and algae (>65.5 mg/L) and about the same for fish, compared to LiOH.