Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1984
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1984
Report date:
1984

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Directive 79/831/EEC, Annex V, Part B
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
400-410-3
EC Name:
-
Cas Number:
25485-88-5
Molecular formula:
C13H16O3
IUPAC Name:
cyclohexyl 2-hydroxybenzoate

Test animals / tissue source

Species:
rabbit
Strain:
New Zealand White

Test system

Vehicle:
unchanged (no vehicle)
Controls:
not specified
Duration of treatment / exposure:
no data
Observation period (in vivo):
72 hours
Number of animals or in vitro replicates:
6

Results and discussion

In vivo

Results
Irritation parameter:
other: irritation index
Basis:
mean
Time point:
other: 1, 24, 48 and 72 hours
Score:
0.7
Max. score:
1
Reversibility:
fully reversible

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information Criteria used for interpretation of results: EU