Registration Dossier

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Administrative data

Description of key information

PG-ds (potassium (R)-[(3-ethoxy-1-methyl-3-oxoprop-1-enyl)amino]phenylacetate) is not a dermal irritant in the rabbit.
PG-ds (potassium (R)-[(3-ethoxy-1-methyl-3-oxoprop-1-enyl)amino]phenylacetate) is an eye irritant in the rabbit.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Additional information

Effects on eye irritation: irritating

Justification for classification or non-classification

Data are conclusive for skin irritation, but not sufficient for classification according to CLP criteria (Regulation (EC) No 1272/2008). No classification is proposed.

Data are conclusive for eye irritation and sufficient for classification according to CLP criteria (Regulation (EC) No 1272/2008). D(-)-alpha-Phenylglycine Dane Salt is considered as an Eye irritant Category 2 (H319: Causes serious eye irritation) according to CLP criteria.

No data is available by inhalation.

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