Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

In the study the test item D(-)-p-HydroxyphenylglycineDaneSalt (K,Methyl) diluted in dimethylsulfoxide was assessed for its possible contact allergenic potential (OECD 429, GLP).

The test item D(-)-p-HydroxyphenylglycineDaneSalt (K,Methyl), was not a skin sensitiser under the test conditions of this study.

(Read-across proposed have been checked using the OECD Toolbox v. 1.1.01).


Migrated from Short description of key information:
By analogy with D(-)-p-Hydroxyphenylglycine Dane Salt (K, Methyl) (CAS 69416-61-1), D(-)-alpha-Phenylglycine Dane Salt is not considered as a skin sensitiser.

Justification for classification or non-classification

Data are conclusive for skin sensitisation, but not sufficient for classification according to CLP criteria (Regulation (EC) No 1272/2008). No data is available by inhalation.

No classification is proposed for sensitisation according to CLP criteria.