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EC number: 930-592-4
CAS number: -
Test substance was assayed for the
mutagenicity by the Bacterial Reverse Mutation Test.
The test was performed according
to B.13/14 Mutagenicity – Reverse Mutation Test Using Bacteria, Council
Regulation (EC) No.440/2008, published in O.J. L 142, 2008. The method
is analogous to the OECD Test Guideline No. 471.
Four indicator Salmonella typhimurium strains TA
98, TA 100, TA 1535, TA 1537 and one indicator Escherichia coli WP2 uvrA
strain were used. The test substance was suspended in ethanol and
assayed in doses of 50 - 5000 µg which were applied to plates in volumes
Two series of experiments were
performed with each strain - without metabolic activation and with a
supernatant of rat liver and a mixture of cofactors.
In the arrangement given above,
the test substance was nonmutagenic for all the used bacterial strains
with as well as without metabolic activation.
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