Registration Dossier

Administrative data

Endpoint:
boiling point
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance is a solid which decomposes before boiling
Cross-reference
Reason / purpose for cross-reference:
data waiving: supporting information
Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2 February 2001
Reliability:
1 (reliable without restriction)
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
1992
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
1995
GLP compliance:
yes
Type of method:
differential scanning calorimetry
Key result
Melting / freezing pt.:
> 97 - < 98 °C
Decomposition:
yes
Decomp. temp.:
> 200 °C

Experiment 1



A small endothermic peak between 41 and 68°C. A large endothermic peak between 85 and 122°C (maximum at 107°C and extrapolated onset temperature at 97°C); this effect is assumed to be caused by melting of the test substance. At > 200°C a small endothermic effect was observed. After the experiment the sample appeared to have been molten and had a yellow colour. Mass loss: 2%. DSC curve: see illustration.


Experiment 2


A small endothermic peak between 40 and 65°C. No changes in appearance and weight. 


Experiment 3


Two endothermic peaks: a small one between 40 and 65°C and a large one between 84 and 113°C. Extrapolated onset temperature of the large peak:98°C. After the experiment the sample had molten; the molten sample was colourless. No significant change in weight.


Experiment 4


Run 1: small endothermic effect  between 39 and 65°C.


Run 2: large endothermic peak  between 73 and 122°C; extrapolated onset temperature: 97°C. Above about 244°C a small endothermic effect was observed. After the experiment the sample appeared to have been molten and had a yellow-brown colour. Mass loss: 0.5%.


Conclusions:
The melting temperature of the substance was determined to be 97°C.
Executive summary:

Differential Scanning Calorimetry was performed (EC A.1 and OECD 102). DSC showed a small endothermic effect at < 70°C, a large endothermic melting effect between about 73-123°C and a small endothermic effect starting at about 200°C. The melting temperature (extrapolated onset temperature of the meling peak) was determined in triplicate obtaining a mean value of 97°C.  Reaction and/or decomposition of the substance occurs from 200°C upwards. 

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion