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Long-term toxicity to aquatic invertebrates

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In a 21-day semi-static reproduction study, the toxicity of SPS-100 to aquatic invertebrate Daphnia magna was evaluated. SPS-100 did not affect reproduction, growth or survival of Daphnia magna at the maximum solubility in test medium (0.2 mg/L) after 21 days of exposure. Therefore, it was concluded that the test substance it is not toxic up to the solubility limit. All criteria for acceptability of the test were met according to OECD guideline No. 211 and the study is considered to be reliable without restrictions.

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In a 21-day semi-static reproduction study, the toxicity of SPS-100 to aquatic invertebrate Daphnia magna was assessed according to OECD Guideline No. 211 (2008) and GLP principles. Nominal concentration was prepared at a loading rate of 100 mg/L and the resulting average concentration measured in the filtered test solutions was 0.2 mg/L. SPS-100 did not affect reproduction, growth or survival of Daphnia magna at the maximum solubility in test medium (0.2 mg/L) after 21 days of exposure. Therefore, it was concluded that the test substance it is not toxic up to the solubility limit. All criteria for acceptability of the test were met according to OECD guideline No. 211 and the study is considered to be reliable without restrictions.