Registration Dossier
Registration Dossier
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EC number: 429-790-9 | CAS number: 137281-39-1
Melting point / freezing point
Administrative data
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 3 to 4 November 1998
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 999
- Report date:
- 1999
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- GLP compliance:
- yes
- Type of method:
- capillary method
Test material
- Reference substance name:
- 4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid
- EC Number:
- 429-790-9
- EC Name:
- 4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid
- Cas Number:
- 137281-39-1
- Molecular formula:
- Hill formula: C15 H14 N4 O3 CAS formula: C15 H14 N4 O3
- IUPAC Name:
- 4-(2-{2-amino-4-oxo-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)benzoic acid
- Test material form:
- solid: particulate/powder
- Details on test material:
- - Compound 202723
- Storage condition of test material: In the dark at ambient temperature
Constituent 1
- Specific details on test material used for the study:
- Compound 202723
- Storage condition of test material: In the dark at ambient temperature
Results and discussion
Melting / freezing point
- Melting / freezing pt.:
- >= 330 - <= 333.5 °C
Any other information on results incl. tables
The melting range of benzoic acid was determined to be 122oC to 124oC which is within acceptable range of 121oC to 124oC, thus the apparatus was considered suitable for use.
A colour change, from light-brown to dark-brown,was noted ca.275oC. Report also lists melting point in Kelvin as 603.15K to 606.65K.
Applicant's summary and conclusion
- Conclusions:
- Melting point was deemed to be in the range of 330-333.5 C
- Executive summary:
The melting range of the material compound 202723 was established with reference to OECD Guideline
102. It was determined that the melting range for the compound 202723 was 603.1K to 606.65K.
Compound 202723 is a light brown powder at ambient room temperature. Ac hange in appearance from a light brown powder to a dark brown powder was observed at 548.15K
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