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EC number: 848-454-6 | CAS number: 1398610-04-2
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 12 to 16 February 2021
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- Batch/Lot number: 451021
Description: White to off white to light yellow powder
Purity: 99.1% - Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 6
- Temp.:
- 25 °C
- Remarks on result:
- other: pH unknown
- Details on results:
- The three independent calibration series and three test item samples were measured. The partition coefficient Pow was determined based on a calibration curves using the eight reference substances. Under the above detailed chromatographic conditions, the main component (Peak I) of the test item had a retention time at 7.63 minutes. Using the linearity equation, the estimated partition coefficient of the test item is LogPow 6.00 ± 0.002 (with 95% confidence interval).
- Conclusions:
- The logPow of the test item is estimated as 6 using HPLC method.
Reference
Description of key information
The logPow of the test item is estimated as 6 using HPLC method.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 6
- at the temperature of:
- 25 °C
Additional information
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