2-Butanone, 1,3,4-trihydroxy-

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2002-12-19

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Reason / purpose for cross-reference:

reference to other study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Version / remarks:

OECD guideline for testing of chemicals no. 105: “Water Solubility”, Adopted July 27, 1995.

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Version / remarks:

EEC Directive 92/69 EEC, Part A, Methods for the determination of physico-chemical
properties, A.6: “Water solubility”. EEC Publication no. L383, December 1992.

Deviations:

no

Principles of method if other than guideline:

NA

GLP compliance:

yes

Type of method:

flask method

Specific details on test material used for the study:

Water solubility was determined on Batch 405045 of the product, purity 81.9% (~80% active ingredient with CAS 533-50-6, ~20% water.

Key result

Water solubility:

>= 1 331 g/L

Temp.:

19.6 °C

pH:

3.1

Details on results:

NA

No remarks

Conclusions:

After the 12 days stirring period, the solution was clear and no undissolved test substance was observed visually. Based on this, it was concluded that the water solubility of (S)-1,3,4-trihydroxybutan-2-one is 1331 g/l at 19.6 ± 1 .0°C. The pH of the water phase was 3.1.

Executive summary:

After the 12 days stirring period, the solution was clear and no undissolved test substance was observed visually. Based on this, it was concluded that the water solubility of (S)-1,3,4-trihydroxybutan-2-one is 1331 g/l at 19.6 ± 1 .0°C. The pH of the water phase was 3.1.

Key value for chemical safety assessment

Water solubility:

1 331 g/L

at the temperature of:

19.6 °C